Atlas of Gross Pathology: With Histologic Correlation by Alan G. Rose

By Alan G. Rose

This atlas offers a entire representation and outline of a variety and variety of pathologic strategies and ailments affecting all of the significant organs of the physique. Emphasis is put on how the anatomic constitution of alternative organs may perhaps make sure the development of involvement by means of disorder procedures and the way such styles may perhaps relief within the right analysis of the gross pathology. at times, a number of illustrations of disorder approaches are given to teach evolution of the sickness. Histologic illustrations of chosen gross lesions also are incorporated the place appropriate. The atlas is illustrated with greater than 1,200 colour photomicrographs. Atlas of Gross Pathology is key for training pathologists, yet may also offer an excellent beginning for surgeons, internists, and obstetricians/gynecologists.

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A. Noteworthy features include massive concentric hypertrophy of left ventricle, inward bulging interventricular septum with mirror image plaque of anterior mitral leaflet, and reactive thickening of anterior leaflet of mitral valve. Note that the mirror image plaque lies more inferiorly than the mitral valve because, during life, tension in its papillary muscles holds the valve at a lower level than after death. B. Transverse biventricular slice showing asymmetric septal hypertrophy (interventricular septum is thicker than free wall of left ventricle).

Qxd 5/12/08 12:21 PM Page 28 1-43. Floppy mitral valve. A. Left atrial view of intact mitral valve showing hemorrhoidal appearance due to multiple hooding of the valve. B. Opened mitral valve showing multiple redundant folds (hoods) on posterior leaflet prolapsing back into the left atrium. Intervening portions of the cusp appear normal. C. Hoods develop at sites of absent fibrosal collagen and expanded spongiosa (loose connective tissue rich in acid mucopolysaccharide). qxd 5/12/08 D 12:21 PM Page 29 1-43.

E. Histologic evidence of myocyte hypertrophy, namely squared off (box car) nuclei. qxd 5/12/08 A 12:23 PM Page 49 1-76. Hypertrophic cardiomyopathy. A. Noteworthy features include massive concentric hypertrophy of left ventricle, inward bulging interventricular septum with mirror image plaque of anterior mitral leaflet, and reactive thickening of anterior leaflet of mitral valve. Note that the mirror image plaque lies more inferiorly than the mitral valve because, during life, tension in its papillary muscles holds the valve at a lower level than after death.

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