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Artificial Sight: Basic Research, Biomedical Engineering, by Mark S. Humayun, James D. Weiland, Gerald Chader, Elias

By Mark S. Humayun, James D. Weiland, Gerald Chader, Elias Greenbaum

Artificial sight is a frontier quarter of modern ophthalmology combining the multidisciplinary skills of surgical ophthalmology, biomedical engineering, organic physics, and psychophysical trying out. Many clinical, engineering, and surgical demanding situations needs to be surmounted sooner than common functional functions could be learned. The target of Artificial Sight is to summarize the state of the art examine during this interesting sector, and to explain many of the current approaches and tasks that can support sufferers in a scientific environment.

The Editors are energetic researchers within the fields of synthetic sight, biomedical engineering and organic physics. they've got bought a number of specialist awards and popularity for his or her paintings. the substitute sight workforce on the Doheny Eye Institute, led via Dr. Mark Humayun, is an international chief during this region of biomedical engineering and medical research.

Key Features

  • Introduces and assesses the state-of-the-art for a huge viewers of biomedical engineers, biophysicists, and scientific researchers
  • Describes advances in microelectronics, microfabrication, surgical implantation, and psychophysical checking out of visible prostheses
  • Outlines the promise of synthetic sight and the demanding situations that has to be met

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Extra resources for Artificial Sight: Basic Research, Biomedical Engineering, and Clinical Advances (Biological and Medical Physics, Biomedical Engineering)

Example text

S735, 1999. 48. Weiland JD, Humayun MS, Suzuki S, et al. Electrically evoked response (EER) from the visual cortex in normal and retinal degenerate dog. Annual meeting of the Association for Research in Vision and Ophthalmology. S783, 1999. 49. Rizzo JF, 3rd, Wyatt J, Loewenstein J, et al. Perceptual efficacy of electrical stimulation of human retina with a microelectrode array during short-term surgical trials. Invest Ophthalmol Vis Sci 2003; 44(12):5362–9. 50. Rizzo JF, 3rd, Wyatt J, Loewenstein J, et al.

17] found that the threshold for stimulation-induced neural damages is determined by a synergetic interaction between charge density and charge per phase, and the limit for safe charge density decreased as charge density increased. With our electrodes, 50 NC/Phase would give a charge density of approximately 110 C/cm2 and the work of McCreery et al. suggests that this combination would not be injurious. Our electrodes were not in direct contact with the neural tissue. Therefore, the limit of electrical charge density may be expected to be higher than that with epiretinal stimulation.

Potential treatments are being investigated in animals, and may some day cure the disease, but are unlikely to be helpful to those who have already lost their sight. These experimental treatments include the following: gene therapy [27], stem cells [28], and RPE and retinal transplantation [29]. Viability of Inner Retinal Cells in Outer Retinal Disease For a retinal prosthesis to be possible, there must be some part of the retina remaining to which the prosthesis can communicate. Morphometric studies of 16 Ameri et al.

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