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Aflatoxins - Biochemistry and Molecular Biology by R. Guevara-Gonzalez

By R. Guevara-Gonzalez

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2007). Multi-tasking on chromatin with the SAGA coactivator complexes, Mutat Res 618, 135-148. R. A. (2007). Function and regulation of aflJ in the accumulation of aflatoxin early pathway intermediate in Aspergillus flavus, Food Addit Contam 24, 1043-1050. W. G. (1999a). Characterization of the promoter for the gene encoding the aflatoxin biosynthetic pathway regulatory protein AFLR, Biochim. Biophys. Acta. 1444, 412-417. , Bhatnagar, D. P. (2011). A hypothesis to explain how LaeA specifically regulates certain secondary metabolite biosynthesis gene clusters, World Mycotoxin Journal 4, 53-58.

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2008). When gene expression by the nonaflatoxigenic A. , unpublished results). Surprisingly, the genes in the AF cluster were still transcribed at normal levels. 3. Signaling factors involved in AF biosynthesis Transcription factors may be activated (or deactivated) through a signal-sensing domain by ligand binding, post-synthetic modifications, or proteolysis. , 2009). This domain participates in several activities including hormone binding, homo- and/or heterodimerization, formation of a complex with a heat-shock protein, and transcriptional activation and repression.

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