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Advantages and Problems with Non-Opioids in Pain Management: by Michael J. Parnham (auth.)

By Michael J. Parnham (auth.)

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Extra resources for Advantages and Problems with Non-Opioids in Pain Management: Vancouver, Canada, August 19, 1996

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1997) Lamina-specific connectivity in the brain: regulation by N-cadherin, neurotrophins, and glycoconjugates. Science 276:1428–1431. Y. (1995) Maggot’s hair and bug’s eye: role of cell interactions and intrinsic factors in cell fate specification. Neuron 14:1–5. M. (2000) Principles of Neural Science, 4 ed. New York: McGraw-Hill. J. (1996) Synaptic activity and the construction of cortical circuits. Science 274:1133–1138. C. , Gasparini P. and Keller F. (2001) Reelin gene alleles and haplotypes as a predisposing factor to Molecular Psychiatry 6:150–159 autistic disorder.

1990; Fig. 7). INBORN GENETIC PROGRAMS CONTROL FORMATION OF NEURONAL CONNECTIONS, WHEREAS ACTIVITY REGULATES THEIR REMODELING One of the most formidable tasks for neurons within the developing CNS is to successfully “find” the appropriate target to establish synaptic connections. In the adult human CNS, over a trillion neurons each connect with, on average, a thousand target cells according to precise patterns essential for proper functioning (Tessier-Lavigne and Goodman, 1996). 7 Time course of neuronal and synaptic remodeling in the rodent cerebral cortex.

1996) Germline mutations in the homeobox gene EMX2 in patients with severe schizencephaly. Nat Genet 12:94–96. R. (1995) T-brain-1: a homolog of brachyury whose expression defines molecularly distinct domains within the cerebral cortex. Neuron 15:63–78. R. (1997) The Role of Hox Genes in Hindbrain Development, 1st ed. New York: Oxford University Press. , Jr. (1982) Neocortical histogenesis in normal and reeler mice: a developmental study based upon [3H] thymidine autoradiography. Dev Brain Res 4:293–302.

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