By Michael J. Parnham (auth.)
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Extra resources for Advantages and Problems with Non-Opioids in Pain Management: Vancouver, Canada, August 19, 1996
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1990; Fig. 7). INBORN GENETIC PROGRAMS CONTROL FORMATION OF NEURONAL CONNECTIONS, WHEREAS ACTIVITY REGULATES THEIR REMODELING One of the most formidable tasks for neurons within the developing CNS is to successfully “ﬁnd” the appropriate target to establish synaptic connections. In the adult human CNS, over a trillion neurons each connect with, on average, a thousand target cells according to precise patterns essential for proper functioning (Tessier-Lavigne and Goodman, 1996). 7 Time course of neuronal and synaptic remodeling in the rodent cerebral cortex.
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